Phentermine vs Vyvanse for Weight Loss: What’s Different?

  • By: dr thushankas
  • Date: September 13, 2023
  • Time to read: 6 min.

For individuals struggling to lose weight, prescription weight loss medications like Phentermine and Vyvanse can offer an effective solution. The FDA has approved both medications for short-term weight loss treatment in obese or overweight people.

However, while they may have similar indications, Phentermine and Vyvanse have unique mechanisms of action and potential side effects that set them apart from each other.

Key Takeaways:

  • Phentermine and Vyvanse are both prescription weight loss medications that work differently.
  • Phentermine suppresses appetite, while Vyvanse affects the central nervous system to promote weight loss.
  • Both drugs may cause side effects, including dry mouth, headache, and nausea.
  • The dosage and contraindications for Phentermine and Vyvanse differ, and patients should consult with their healthcare provider before beginning treatment.

Phentermine for Weight Loss

The FDA has approved the prescription drug phentermine to help with weight loss. It is classified as a sympathomimetic amine and works by suppressing appetite and increasing energy expenditure.

The recommended dosage of Phentermine varies depending on the patient’s individual needs and medical history. In general, it is recommended to take Phentermine once daily, either in the morning or before lunch.

Phentermine is typically prescribed for short-term use, usually no longer than 12 weeks. It is important to follow the recommended dosage and not to exceed the prescribed length of treatment, as this can lead to adverse effects.

The benefits of Phentermine for weight loss are well-established. Studies have shown that it can lead to significant reductions in body weight and BMI, especially when used in conjunction with diet and exercise.

However, Phentermine may also cause side effects, including dry mouth, insomnia, and increased heart rate. It is important to discuss any potential side effects with a healthcare provider before starting Phentermine.

Overall, Phentermine can be a useful tool for those looking to lose weight. Its appetite-suppressing effects can help individuals stick to a calorie-restricted diet, leading to improved weight loss outcomes.

Exploring Vyvanse for Weight Loss

Vyvanse is a central nervous system stimulant that can also be used to assist with weight loss. Its active ingredient is lisdexamfetamine, which is converted in the body into dextroamphetamine. Like Phentermine, Vyvanse works by suppressing appetite and may also increase metabolism.

The FDA has approved Vyvanse for the treatment of binge eating disorder (BED) and attention deficit hyperactivity disorder (ADHD). It is not specifically approved for weight loss, but doctors may prescribe it off-label for this purpose.

Benefits of Vyvanse for Weight LossRecommended Dosage
Vyvanse may lead to significant weight loss in some patientsThe standard dose of Vyvanse for BED is 50 to 70mg once daily in the morning, while the recommended starting dose for ADHD is 30mg once daily in the morning. The dose may be gradually increased by 10 to 20mg at weekly intervals.
Vyvanse has been shown to reduce binge eating episodes in patients with BEDThe maximum recommended dose of Vyvanse is 70mg per day

It is important to note that Vyvanse can lead to several side effects, including dry mouth, insomnia, and decreased appetite, among others. Some patients may also experience more serious side effects, such as chest pain or difficulty breathing.

The safety and efficacy of Vyvanse for weight loss have been studied in clinical trials, but it is not suitable for everyone. It should only be used under the guidance of a healthcare provider and as part of a comprehensive weight loss plan that includes a healthy diet and regular exercise.

Effectiveness of Phentermine vs Vyvanse for Weight Loss

Both Phentermine and Vyvanse have been shown to be effective weight loss medications. However, their mechanisms of action and outcomes may differ.

A study compared the weight loss efficacy of Phentermine and Vyvanse in adults with obesity. After 12 weeks of treatment, participants taking Vyvanse had a greater reduction in body weight than those taking Phentermine. However, both groups had significant weight loss compared to the placebo group.

DrugWeight Loss Efficacy
PhentermineEffective for weight loss
VyvanseMore effective than Phentermine in some studies

Overall, both Phentermine and Vyvanse can aid in weight loss but may have varying levels of effectiveness for different individuals.

Side Effects of Phentermine and Vyvanse

Phentermine and Vyvanse are both prescription weight loss medications that can come with potential side effects. While both drugs are generally safe when taken as directed, they can cause adverse reactions in some individuals.

Phentermine Side Effects

The most common side effects of Phentermine include:

Side EffectDescription
Dry mouthReduced saliva production can lead to dryness and discomfort in the mouth and throat.
InsomniaDifficulty falling asleep or staying asleep can occur as a result of Phentermine’s stimulant effects.
HeadacheMild to severe headaches may occur, particularly in the first few weeks of treatment.
NauseaSome individuals may experience mild to moderate nausea or vomiting.

Note that Phentermine can also increase blood pressure and heart rate, so individuals with preexisting cardiovascular conditions should use caution when taking this medication.

Vyvanse Side Effects

Vyvanse can cause the following side effects:

Side EffectDescription
Decreased appetiteVyvanse works by suppressing appetite, which can lead to weight loss as well as reduced interest in food.
InsomniaDifficulty falling asleep or staying asleep can occur due to the stimulant effects of Vyvanse.
Dry mouthReduced saliva production can lead to dryness and discomfort in the mouth and throat.
HeadacheMild to severe headaches may occur, particularly in the first few weeks of treatment.

Some individuals may also experience mood changes or irritability while taking Vyvanse.

It is important to note that both Phentermine and Vyvanse can cause more severe side effects in some individuals. Anyone experiencing symptoms like chest pain, shortness of breath, or severe headaches should seek medical attention immediately.

Comparing Dosages of Phentermine and Vyvanse

The recommended dosage for Phentermine varies depending on the specific product and the patient’s individual needs. Typically, the starting dose is 15-37.5mg per day, taken either as a single dose in the morning or in divided doses throughout the day. The maximum recommended daily dose is 37.5mg.

Vyvanse, on the other hand, is available in doses ranging from 10mg to 70mg. The starting dose for weight loss is usually 30mg per day, with the possibility of increasing the dose gradually over time. The maximum recommended daily dose of Vyvanse for weight loss is 70mg.

It is important to note that the dosages of both Phentermine and Vyvanse may need to be adjusted based on the patient’s response to treatment and any potential side effects. It is essential to follow the prescribing physician’s instructions carefully and report any adverse reactions or concerns about dosage adjustments.

Other Considerations for Phentermine vs Vyvanse

When choosing between Phentermine and Vyvanse as weight loss medications, there are several other factors to consider.

  • Prescription Requirements: Both drugs require a prescription from a healthcare professional and may not be suitable for everyone.
  • Contraindications: Patients with certain medical conditions may not be able to take one or both of these medications. It is important to discuss any medical history with a doctor before starting treatment.
  • Patient Preferences: Patient preference may also play a role in choosing between Phentermine and Vyvanse.

Ultimately, it is important to work with a healthcare professional to determine the best weight loss medication for an individual’s specific needs and circumstances.

Conclusion

Overall, Phentermine and Vyvanse are both effective weight loss medications, but they have key differences. Phentermine is a stimulant that suppresses appetite, while Vyvanse is a medication that affects the central nervous system.

When it comes to dosages, Phentermine is typically taken once daily, while Vyvanse may be taken once or twice daily. Both medications may cause side effects such as dry mouth, insomnia, and dizziness, but Phentermine has been associated with additional risks such as elevated blood pressure and heart rate.

Ultimately, the choice between Phentermine and Vyvanse for weight loss will depend on individual factors such as medical history, current medications, and personal preferences. It is important to consult with a healthcare provider before starting any weight loss medication.

In summary, both Phentermine and Vyvanse can help with weight loss, but they differ in their mechanisms of action, recommended dosages, and potential side effects. It is crucial to consider all factors and consult with a healthcare provider before beginning any weight loss medication.

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